Quality of Research
Documents Reviewed
The documents below were reviewed for Quality of Research. The research point of
contact can provide information regarding the studies reviewed and the availability
of additional materials, including those from more recent studies that may have been conducted.
Study 1Azrin, N. H., McMahon, P. T., Donohue, B., Besalel, V. A., Lapinski, K. J., Kogan, E. S., et al. Behavior therapy for drug abuse: A controlled treatment outcome study. Behaviour Research and Therapy, 32, 857-866. Study 2Azrin, N. H., Acierno, R., Kogan, E. S., Donohue, B., Besalel, V. A., & McMahon, P. T. Follow-up results of supportive versus behavioral therapy for illicit drug use. Behaviour Research and Therapy, 34, 41-46. Study 3Azrin, N. H., Donohue, B., Besalel, V. A., Kogan, E. S., & Acierno, R. Youth drug abuse treatment: A controlled outcome study. Journal of Child & Adolescent Substance Abuse, 3, 1-15. Study 4Azrin, N. H., Donohue, B., Teichner, G. A., Crum, T., Howell, J., & DeCato, L. A. A controlled evaluation and description of individual-cognitive problem solving and family-behavior therapies in dually diagnosed conduct-disordered and substance-dependent youth. Journal of Child & Adolescent Substance Abuse, 11, 1-41.
Supplementary Materials DeCato, L. A., Donohue, B., Azrin, N. H., & Teichner, G. A. Satisfaction of conduct-disordered and substance-abusing youth with their parents. Behavior Modification, 25, 44-61.
Donohue, B., & Azrin, N. H. Family behavior therapy. In E. Wagner & H. Waldron (Eds.), Innovations in adolescent substance abuse interventions. Tarrytown, New York: Pergamon.
Donohue, B., & Azrin, N. H. Family behavior therapy in a conduct-disordered and substance-abusing adolescent: A case example. Clinical Case Studies, 1, 299-323.
Donohue, B., Azrin, N. H., Lawson, H., Friedlander, J., Teichner, G., & Rindsberg, J. Improving initial session attendance of substance abusing and conduct disordered adolescents: A controlled study. Journal of Child & Adolescent Substance Abuse, 8, 1-14.
Donohue, B., Azrin, N. H., Strada, M. J., Silver, N. C., Teichner, G., & Murphy, H.. Psychometric evaluation of self and collateral Timeline Follow-Back reports of drug and alcohol use in a sample of drug-abusing and conduct-disordered adolescents and their parents. Psychology of Addictive Behaviors, 18, 184-189.
Donohue, B., DeCato, L. A., Azrin, N. H., & Teichner, G. A. Satisfaction of parents with their conduct-disordered and substance-abusing youth. Behavior Modification, 25, 21-43.
Donohue, B., Teichner, G., Azrin, N., Weintraub, N., Crum, T. A., Murphy, L., et al. Initial reliability and validity of the Life Satisfaction Scale for Problem Youth in a sample of drug abusing and conduct disordered youth. Journal of Child and Family Studies, 12, 453-464.
Family Behavior Therapy Modules 1-8
Outcomes
Outcome 1: Drug use |
Description of Measures
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Illicit drug use was measured by urinalysis, self-report, and family member reports. In most studies, Timeline Followback methods were used for self-reports and family member reports.
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Key Findings
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Three randomized controlled trials showed reduced illicit drug use among FBT participants. A 12-month trial with youth and adults showed that FBT clients were significantly less likely to report using any illicit drugs than supportive therapy clients in months 2 through 12 of treatment (p < .001). At the end of treatment, the average number of days of use each month was 2.1 for FBT clients, compared with 5.4 for supportive therapy clients (p < .02). At an average of 9 months after treatment termination, 71% of supportive therapy clients were using illicit drugs, compared with 42% of FBT clients (p < .02).
In a study of 26 youth, drug use decreased 73% over 6 months of treatment for those in FBT but did not change among those in supportive therapy (p < .02).
A study of youth with conduct disorder compared FBT with individual cognitive therapy. Both samples significantly decreased substance use from an average of 14 days per month to 9 days per month over 6 months of treatment (p < .001). Six months after treatment completion, both groups used drugs about 8 days per month, on average (p < .005).
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Studies Measuring Outcome
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Study 1, Study 2, Study 3, Study 4
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Study Designs
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Experimental
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Quality of Research Rating
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2.9
(0.0-4.0 scale)
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Outcome 2: Alcohol use |
Description of Measures
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Alcohol use was measured by self-reports and other measures. In most cases, Timeline Followback methods were used.
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Key Findings
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In a randomized controlled trial of adults and youth, adult FBT clients decreased frequency of alcohol use by nearly 50%, from an average of 7 days per month to 3.8 days per month over 12 months of treatment, while frequency of alcohol use did not change for those in supportive therapy (p < .001). Youth participating in FBT decreased alcohol use from an average of 2.2 to 1.5 days per month over 6 months of treatment, while those in supportive therapy increased use from an average of 3.2 to 4.5 days per month (p < .05). In a study of youth with conduct disorder, neither FBT nor individual cognitive therapy affected alcohol use.
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Studies Measuring Outcome
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Study 1, Study 3, Study 4
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Study Designs
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Experimental
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Quality of Research Rating
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2.7
(0.0-4.0 scale)
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Outcome 3: Family relationships |
Description of Measures
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Family relationships were measured using the Marital/Couple Happiness Scale, the Parent Satisfaction Scale, and the Youth Satisfaction Scale, which ask respondents to report satisfaction with family members and marital relationships on a scale from 0 to 100 percent.
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Key Findings
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In a sample of youth who used substances, parents' mean satisfaction with youth in FBT increased 30% from pre- to posttreatment, while parents' mean satisfaction with youth in supportive counseling did not change. In a study of youth with conduct disorder, parents' mean satisfaction with youth increased nearly 30% from pre- to posttreatment (p < .001). Youth mean satisfaction with parents increased approximately 11% from pre- to posttreatment (p < .001). Changes in the conduct-disordered youth sample were similar to changes observed in a comparison sample of youth receiving individual cognitive therapy. In another study with a sample of adults, significant changes in marital happiness were not observed.
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Studies Measuring Outcome
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Study 3, Study 4
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Study Designs
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Experimental
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Quality of Research Rating
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2.8
(0.0-4.0 scale)
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Outcome 4: Depression |
Description of Measures
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Depression was measured with the Beck Depression Inventory.
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Key Findings
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In a sample of youth and adults, depression decreased more in FBT participants compared with participants in a nonbehavioral intervention. Beck Depression Inventory scores dropped from an average of 17.9 to 7.2 for FBT participants and from 13.5 to 8.9 for clients in supportive therapy (p < .01). Among youth who used substances, Beck Depression Inventory scores decreased significantly in FBT participants but not in supportive therapy clients. However, supportive therapy clients were also less depressed pretreatment (mean score = 6.5) compared with the FBT clients (mean score = 15.2). Posttreatment, the average score for FBT clients was 5.5, compared with 6.5 for supportive therapy clients (p < .05). Scores among the youth with conduct disorder dropped to a subclinical level of depression posttreatment (p < .001). Posttreatment levels were maintained at 6-month follow-up. Changes in the FBT sample were comparable to those for clients in individual cognitive therapy.
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Studies Measuring Outcome
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Study 1, Study 3, Study 4
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Study Designs
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Experimental
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Quality of Research Rating
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3.2
(0.0-4.0 scale)
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Outcome 5: Employment/school attendance |
Description of Measures
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Days employed or attending school were measured by self-report on the Timeline Followback Interview.
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Key Findings
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In a study of youth and adults, the mean percentage of days employed or in school over the past month increased from 52.2% to 73.6% among FBT clients and decreased slightly from 67.8% to 64.5% among supportive therapy clients (p < .001). Among youth who used substances, mean school/work attendance increased from 50.2% to 65.4% for FBT clients, while it decreased from 79.5% to 68.4% among supportive therapy clients (p < .05). Multiple measures of work and school attendance showed improvement for youth with conduct disorder who participated in FBT. Average hours worked per month over the last 6 months increased from 6.38 to 16.71 (p < .01), a change comparable to that observed for youth in individual cognitive therapy.
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Studies Measuring Outcome
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Study 1, Study 3, Study 4
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Study Designs
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Experimental
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Quality of Research Rating
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2.7
(0.0-4.0 scale)
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Outcome 6: Conduct disorder symptoms |
Description of Measures
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Conduct problems were measured by standardized behavior checklists, self-report, parent reports, and arrest records.
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Key Findings
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Among youth who used substances, the mean number of problems reported on the Quay Problem Behavior Checklist decreased from 22.5 to 14.3 for those in FBT but remained essentially unchanged for those in supportive therapy (p < .05). Multiple measures of conduct problems showed significant pre- to posttreatment improvements in youth diagnosed with conduct disorder. Average scores on the Achenbach Child Behavior Checklist decreased from 74.44 to 63.55. Posttreatment improvement was maintained at 6-month follow-up. Improvements observed in FBT clients were similar to those observed for clients in individual cognitive therapy.
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Studies Measuring Outcome
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Study 3, Study 4
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Study Designs
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Experimental
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Quality of Research Rating
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2.9
(0.0-4.0 scale)
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Study Populations
The following populations were identified in the studies reviewed for Quality of
Research.
Study
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Age
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Gender
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Race/Ethnicity
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Study 1
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13-17 (Adolescent) 18-25 (Young adult) 26-55 (Adult)
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68.3% Male 31.7% Female
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91% White 9% Race/ethnicity unspecified
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Study 2
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13-17 (Adolescent) 18-25 (Young adult) 26-55 (Adult)
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74.3% Male 25.7% Female
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87.8% White 12.2% Race/ethnicity unspecified
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Study 3
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13-17 (Adolescent)
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77% Male 23% Female
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81% White 19% Race/ethnicity unspecified
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Study 4
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13-17 (Adolescent)
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82.1% Male 17.9% Female
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79% White 16% Hispanic or Latino 3% Race/ethnicity unspecified 2% Black or African American
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Quality of Research Ratings by Criteria (0.0-4.0 scale)
External reviewers independently evaluate the Quality of Research for an intervention's
reported results using six criteria:
For more information about these criteria and the meaning of the ratings, see Quality of Research.
Outcome
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Reliability
of Measures
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Validity
of Measures
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Fidelity
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Missing
Data/Attrition
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Confounding
Variables
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Data
Analysis
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Overall
Rating
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1: Drug use
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3.6
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3.0
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2.5
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2.0
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3.0
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3.0
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2.9
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2: Alcohol use
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3.0
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3.0
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2.5
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2.0
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3.0
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2.5
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2.7
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3: Family relationships
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3.0
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3.5
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2.5
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2.0
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3.0
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3.0
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2.8
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4: Depression
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4.0
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4.0
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2.5
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2.0
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3.5
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3.0
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3.2
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5: Employment/school attendance
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3.0
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2.5
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2.5
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2.0
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3.0
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3.0
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2.7
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6: Conduct disorder symptoms
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3.5
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3.5
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2.5
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2.0
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3.0
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3.0
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2.9
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Study Strengths Researchers used multiple standardized, reliable, and valid measures. The more recent research provided systematic assessment of the reliability and validity of urinalysis and of the Timeline Followback approach, as well as other standardized measures of life and relationship satisfaction. Both self-reports and significant-other reports of treatment outcome were employed, and the use of multiple informants enhanced validity.
Study Weaknesses The studies of youth and conduct-disordered youth had some overlap of samples. Both treatment intervention groups in the study of conduct-disordered youth showed comparable levels of improvement. Further work is necessary to determine whether FBT influences drug use with this population. Fidelity checks generally were not quantified. Statistical tests were repeated without correction for inflated Type 1 error rate. One-tailed tests were used. However, as indicated by the investigators, the observed pattern of results was consistent across data sets analyzed, and most associated p values were highly reliable. No details were provided on how researchers adjusted for missing data. Differences between participants who dropped out and those who completed treatment were not adequately assessed. In some studies, the researchers failed to report psychometric support for some of their measures.
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